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Molecular mechanisms of neurodegeneration related to C9orf72 hexanucleotide repeat expansion

* *See also a 2011 report indicating that spironolactone did not extend survival times of dogs with advanced heart failure

PDHA1 hyperacetylation-mediated lactate overproduction promotes sepsis-induced acute kidney injury via Fis1 lactylation

Although certain trials demonstrate benefits in insulin sensitivity and hepatic steatosis, others report neutral outcomes

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